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CD8a/a

Immune v2

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High hierarchy

T cells

Low hierarchy

CD8a/a

Description

unconventional T lymphocytes with CD8 alpha/alpha homodimers binding MHC molecules

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Curated Markers

ZNF683
GeneCards NCBI Ensembl
GNG4
GeneCards NCBI Ensembl
PDCD1
GeneCards NCBI Ensembl

Top Model Markers

CD27
GeneCards NCBI Ensembl
NUCB2
GeneCards NCBI Ensembl
LEF1
GeneCards NCBI Ensembl
ZNF683
GeneCards NCBI Ensembl
PRKCH
GeneCards NCBI Ensembl
TRBV10-2
GeneCards NCBI Ensembl
IGKJ5
GeneCards NCBI Ensembl
AC006115.2
GeneCards NCBI Ensembl
AC018754.1
GeneCards NCBI Ensembl
PAGE5
GeneCards NCBI Ensembl

Datasets

Park et al. 2020
PubMed

Tissues

  • Thymus

Ontology CL:0000084

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About Teichmann Lab in the Cambridge Stem Cell Institute

The Teichmann Lab is based in the Cambridge Stem Cell Institute of the University of Cambridge. The Teichmann lab uses cell-atlasing and cellular genetics to map cells in the human body combining cutting-edge methodologies and computational approaches.

About CellTypist

CellTypist was first developed as a platform for exploring tissue adaptation of cell types using scRNA-seq semi-automatic annotations. Now it's an open source tool for automated cell type annotations as well as a working group in charge of curating models and ontologies.

Citation

If you use any resources or service here, please cite:

Automatic cell-type harmonization and integration across Human Cell Atlas datasets. Cell 186, 5876–5891.e20 (2023). Link

Cross-tissue immune cell analysis reveals tissue-specific features in humans. Science 376, eabl5197 (2022). Link

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Working Group
  • Simone Webb, Laura Jardine (Haniffa Lab)
  • Benjamin Stewart, Kelvin Tuong (Clatworthy Lab)
  • Regina Hoo (Vento-Tormo Lab)
  • Chuan Xu, Cecilia Domínguez Conde, Kylie James, Jongeun Park, Elo Madissoon, Waradon Sungnak, Rasa Elmentaite, Peng He (Teichmann Lab)